Objective: Anomaly scan at the second trimester provides
the detail anatomical study of fetus. Any structural or
morphological defects detected prenatally guides the
parents and doctors for further counseling. The main
objective of this study was to detect the fetal congenital
anomalies in high risk patients at 18-22 weeks and highlight
the effectiveness of prenatal ultrasound examination.

Materials and Methods: This was a hospital based
descriptive study done during the period of 2017
January to 2019 January in the department of Radiology,
ultrasound unit, Pokhara Academy of Health Sciences,
Nepal. Pregnant women who were first examined and
evaluated by the Obstetrician during the ante-natal check
up (ANC) either by asking the patient history or by mother
age or any symptoms or chance of being abnormalities
or high risk patients during that time frame (18-22
weeks) were enrolled for the study. Maternal age, parity,
any history of previous anomalies, previous history of
miscarriage/Intra Uterine Fetal Demise ( IUFD) or any
exposure to radiation or drugs, history of other disease
were recorded during the filling of consent form. High risk
patients were identified by the Obstetrician and anomaly
examination was prescribed at second trimester (18-20
weeks). Descriptive analysis was done using SPSS 20.

Results: There were two hundred and twenty four patients
who had undergone anomaly (targeted fetal anatomy)
examination which were referred for “anomaly scan” from
the gynecology and obstetrics department during that period.
Among all the cases, fourteen cases had anomalies detected
during the scan (18-22 weeks). Out of which seven cases
had central nervous system related anomalies, two cases
had skeletal deformities (dysplasia), two case had urinary
tract related anomalies, one had lungs related anomalies
and one had single umbilical artery with polyhydroamnios
associated with duodenal atresia and one case had
malformation of lymphatic system ( cystic hygroma )

Conclusion:Our study revealed that ultrasound scan
performed between 18-22 weeks of pregnancy is
effective in diagnosing major fetal abnormalities in the
high-risk patients.

Keywords: Anomaly scan, Congenital anomalies, Second trimester, Prenatal, Ultrasound