Background : Neutrophil lymphocyte Ratio (NLR)
and Platelet lymphocyte Ratio (PLR) are an indicator
of the status of inflammation. The objective of this
study was to evaluate the relationship between
recipient pre-operative Neutrophil lymphocyte
Ratio (NLR) and Platelet lymphocyte Ratio (PLR)
with delayed graft function in the kidney transplant

Methods: The preoperative full blood
count, data regarding patient demographics and
postoperative graft function was retrospectively
evaluated from the database of our institution.
All statistical calculations were carried out using
SPSS 20.0 version(SPSS Inc., Chicago, IL,
USA).A p-value<0.05 was considered statistically

Results: 289 patients were included
in this study. DGF occurred in 33 cases. Elevated
preoperative NLR had a sensitivity of 75.75% and
specificity of 76.56% whereas elevated preoperative
PLR had a sensitivity of 72.72% and specificity of
58.20% for predicting DGF. The area under the ROC
curve was found to be 0.762 and 0.655 for NLR and
PLR, respectively. Multivariate analysis showed
NLR>3.5 and PLR>120 independently responsible
for DGF.

Conclusion: Recipient preoperative
NLR and PLR can predict the occurrence of DGF
following DBD renal transplantation. In addition,
NLR is better than PLR in predicting DGF. DGF
prolongs the total ICU and in-hospital stay.

Keywords: Neutrophil lymphocyte Ratio, Platelet lymphocyte Ratio, Delayed graft function, Kidney transplantation, Inflammation