Introduction: Signs and symptoms of Systemic Inflammatory Response Syndrome are frequently observed in post-operative and surgery wards. Inflammation and infection after major operations may lead to organ dysfunction and failure. When Systemic Inflammatory Response Syndrome progresses to multiple organ failure, the mortality is significantly high, depending on the number of failed organs. This study emphasizes to focus on Systemic Inflammatory Response Syndrome and sepsis in postoperative patients, so that timely care to such patients leads to decreased hospital stay. Financial to the patient can also be reduced.

Materials and Methods: This is a prospective observational study. Patients in surgical and post-operative wards were categorized as having systemic inflammatory response syndrome, if following two or more criteria were present: pulse rate: >90 beats/min, respiratory rate: >20 breaths/min, temperature: > 38°C or < 36°C, total leucocytes count: > 12,000/μL or < 4,000/μL. Patients with Systemic Inflammatory Response Syndrome were compared with outcomes of surgery like length of hospital stay and mortality with other similar patients.

Results: There were 120 post-operative cases of elective surgeries under general anaesthesia with 42 males and 78 females. Eighteen (15%) had Systemic Inflammatory Response Syndrome. No mortality was recorded due to the syndrome. Among total patients with the inflammatory syndrome, 61.11% were males compared to 38.89% females. Duration of the surgery was significantly associated with the syndrome, as 66.67% of those who developed Systemic Inflammatory Response Syndrome had undergone surgery for more than an hour.

Conclusion: Incidence of Systemic Inflammatory Response Syndrome among elective post-operative patients was greater in males and it increased with the total duration of the surgery

Keywords: Postoperative, SIRS, morbidity, organ failure