Introduction: Chronic Kidney Disease stage 5 is diagnosed when glomerular filtration rate is <15.0ml/ min/1.73m2 . Chronic kidney disease is an increasingly recognized major public health problem. The aim of our study was to estimate the socio-demographic profiles, etiologies and complications of chronic kidney disease stage 5 and associated co-morbidities in patients attending a referral hospital of Gandaki Province.

Materials and Methods: An observational cross sectional study was carried out in the Department of Medicine, Pokhara Academy of Health Sciences, during the period from August 2020 to February 2021. Chronic kidney disease patients undergoing maintenance hemodialysis in dialysis unit willing to participate were included. The data were collected and were analyzed using SPSS version 25.0 software.

Results: Hundred patients were taken into study. Most common causes of chronic kidney disease were chronic glomerulonephritis followed by diabetes mellitus and hypertension. Most common complications during dialysis were chills and rigor followed by muscle cramps, hypotension, backache, hypertension and hypoglycemia. Most common complications of chronic kidney disease were anemia (91%) followed by cardiovascular diseases and hypertension. It was observed that a proportion (5%) of patients developed stroke.

Conclusion: Chronic glomerulonephritis was found to be the most frequent cause of CKD, followed by diabetes and hypertension. Anemia was found to be most common feature among CKD patients.

Keywords: Chronic Kidney Disease, Hemodialysis,, Glomerulonephritis