Introduction: Diabetes Mellitus is a common and
serious global health problem and is associated
with the complications such as cardiovascular
disease, nephropathy, retinopathy and neuropathy,
which can lead to severe mortality and morbidity.
The purpose of this study was to find out the healthrelated quality of life patients with diabetes mellitus.
Descriptive cross-sectional research design was
used among 116 patients with diabetes mellitus in
Diabetes, Thyroid and Endocrinology Care Center,
Pokhara via Systematic sampling.

Materials and Methods: Data was collected using
structured World Health Organization Quality of
Life Instrument- Short form: WHOQOL-BREF
tool and analyzed by using computer package with
Statistical Package for Social Science software
version 16. In inferential statistics t- test and
ANOVA test was used to measure the association
between selected demographic variables and overall
HRQOL as well as all the domains at 5 percent level
of significance.

Results: The significant association was observed
between physical, psychological, social and
environment domain with presence of comorbid
illness and complications. The study found that
patients with diabetes mellitus had higher health
related quality of life in environment domain but
lower in social domain. Age below 54 years, male,
duration of disease less than 10 years, living in a
nuclear family and employed respondent had higher
quality of life.

Conclusion: The study concluded the overall
HRQOL is good in patient less than 54 years, male,
married, patient having family history of diabetes,
duration of diabetes less than 10 years, absence of
comorbidity and complications.


Keywords: diabetes mellitus, domains, health related quality of life