Abstract

Background:
Penile cancer is an aggressive and mutilating disease which
deeply affects self-esteem and daily life of the patient. Penile
cancer mostly affects the elderly, seen in people in their sixties
and seventies. Occurrence in younger age is a need of research
of penile neoplasia in young non-circumcised patients.



Materials and Method:


This is a three-year retrospective
study. Data was extracted from the Department of Pathology
and Medical Record section of B.P. Koirala Memorial Cancer
Hospital. All histologically proven cases were included.


The objective of this study was to assess clinical histo-
pathological profile of penile carcinoma.


Results. A total of 114 malignant cases were included out of which most
common age group involved was 50-60 years with mean age
of presentation being 51.6 years. Glans was the commonest
site of involvement in 59 cases (51.7%). Well-differentiated
squamous cell carcinoma was the most common type (71%).
Forty nine patients (43%) presented when the mass size was
4-6 cm and 44 (39%) came with 2-4cm and rest less than 2
cm. Lymphvascular invasion was seen in 15 (13%) out of
114 cases and perineural invasion was seen only in 5 (4.3%)
cases. 20 cases (17.5%) had lymphnodes positive which are
less than 5 lymphnode positive and five (4.3%) had more
than 5 lymphnodes positive.


Conclusion.


Early diagnosis and intervention of the patient ensure high probability of getting
cured because the stage at presentation appears to be the most
vital prognostic indicator for survival.

Keywords: Penile, Squamous cell carcinoma, Malignant